Description

tert-Butyl 4-(2-Bromobenzyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core protected by a Boc (tert-butoxycarbonyl) group and functionalized with a 2-bromobenzyl moiety. This compound is crucial for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel drug candidates. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the efficient and cost-effective manufacturing of complex molecules.
• Library Synthesis: A valuable building block for the generation of diverse compound libraries for high-throughput screening (HTS) in early-stage drug discovery.
• Custom Synthesis: Serves as a starting material for the custom synthesis of specialized fine chemicals and research compounds.

Basic Information

Item	Detail
Product Name	tert-Butyl 4-(2-Bromobenzyl)Piperazine-1-Carboxylate
CAS No.	460094-85-3
Molecular Formula	C16H23BrN2O2
Molecular Weight	355.27 g/mol
Synonyms	1-Boc-4-(2-Bromobenzyl)Piperazine; 4-(2-Bromobenzyl)Piperazine-1-Carboxylic Acid tert-Butyl Ester; tert-Butyl 4-[(2-Bromophenyl)methyl]piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(2-bromobenzyl)piperazine; N-Boc-4-(2-Bromobenzyl)piperazine; 460094-85-3; 4-(2-Bromobenzyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Bromobenzyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.