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8-[(2-Ethyl-1-Piperidinyl)Methyl]-7-Hydroxy-3-(2-Naphthyloxy)-2-(Trifluoromethyl)-4H-Chromen-4-One CAS NO 459413-81-1
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CAS No.:459413-81-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
8-[(2-Ethyl-1-Piperidinyl)Methyl]-7-Hydroxy-3-(2-Naphthyloxy)-2-(Trifluoromethyl)-4H-Chromen-4-One is a high-purity, complex organic compound belonging to the chromen-4-one (chromone) class, distinguished by its trifluoromethyl and naphthyloxy substituents. This compound is of significant interest for its potential as a key pharmaceutical intermediate or advanced research chemical in drug discovery programs. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing novel therapeutic agents.
Application
- Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or inflammatory pathways.
- Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
- Biochemical Tool Compound: Acts as a selective inhibitor or modulator in pharmacological assays to study specific enzyme or receptor functions.
- Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, fluorinated molecules with high added value.
- Reference Standard: Provides an authenticated material for analytical method development, validation, and quality control in regulatory submissions.
Basic Information
| Product Name | 8-[(2-Ethyl-1-Piperidinyl)Methyl]-7-Hydroxy-3-(2-Naphthyloxy)-2-(Trifluoromethyl)-4H-Chromen-4-One |
| CAS No. | 459413-81-1 |
| Molecular Formula | C28H26F3NO4 |
| Molecular Weight | 497.51 g/mol |
| Synonyms | 7-Hydroxy-3-(2-naphthyloxy)-2-(trifluoromethyl)-8-[(2-ethyl-1-piperidinyl)methyl]-4H-chromen-4-one; 8-[(2-Ethylpiperidin-1-yl)methyl]-7-hydroxy-3-(naphthalen-2-yloxy)-2-(trifluoromethyl)-4H-chromen-4-one; 459413-81-1; Chromone derivative with piperidinylmethyl and naphthyloxy groups; 2-(Trifluoromethyl)-3-(2-naphthyloxy)-7-hydroxy-8-[(2-ethyl-1-piperidinyl)methyl]-4-chromone |
| EINECS | Contact for details |
Quality Control
Our 8-[(2-Ethyl-1-Piperidinyl)Methyl]-7-Hydroxy-3-(2-Naphthyloxy)-2-(Trifluoromethyl)-4H-Chromen-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific client or regulatory requirements.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under inert atmosphere when not in use to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | Off-white to light yellow powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.5% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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