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C30(-Hydroxy) Ceramide (D18:1/30:0) CAS NO 457100-08-2


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CAS No.:457100-08-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

C30(-Hydroxy) Ceramide (D18:1/30:0) is a specific, long-chain ceramide molecule characterized by a sphingosine base (D18:1) and a 30-carbon α-hydroxy fatty acid. This precise molecular structure is critical for advanced research and development in lipid biochemistry and skin biology. It is primarily utilized by R&D scientists and formulators in the cosmetics, dermatology, and pharmaceutical industries for studying skin barrier function, developing high-performance skincare products, and exploring novel therapeutic pathways.

Application

  • Advanced Cosmetic & Skincare Formulations: As a key active ingredient in premium anti-aging, moisturizing, and barrier-repair serums, creams, and lotions.
  • Dermatological Research: For in-vitro and ex-vivo studies investigating skin barrier integrity, lipid metabolism, and ceramide-mediated signaling pathways.
  • Pharmaceutical Development: Exploration of its role in drug delivery systems and as a potential therapeutic agent for skin disorders like atopic dermatitis and psoriasis.
  • Biomimetic Membrane Studies: Used in the construction of artificial lipid bilayers and vesicles to model and study cellular membrane properties and interactions.
  • Reference Standard: Serves as a high-purity analytical standard for the quantification and qualification of ceramides in complex biological or product matrices via LC-MS or HPLC.
  • Nutraceuticals: Investigated for inclusion in specialized supplements targeting skin health from within.

Basic Information

Product Name C30(-Hydroxy) Ceramide (D18:1/30:0)
CAS No. 457100-08-2
Molecular Formula C48H95NO4
Molecular Weight 750.3 g/mol
Synonyms N-[(2S,3R,4E)-1,3-Dihydroxyoctadec-4-en-2-yl]-2-hydroxy-triacontanamide; (2S,3R,4E)-2-N-(2-Hydroxytriacontanoyl)-1,3-dihydroxysphing-4-ene; α-Hydroxy-C30-ceramide (d18:1/30:0); Ceramide NS with α-hydroxy C30 fatty acid; C30 α-Hydroxy fatty acid sphingosine ceramide; N-(α-Hydroxytriacontanoyl)-D-erythro-sphingosine; Lipoceramide D18:1/30:0(2OH).
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Quality Control

Our C30(-Hydroxy) Ceramide is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for research and formulation. A detailed Certificate of Analysis (COA) documenting purity, assay, and impurity profiles is provided with every shipment. We support compliance with relevant guidelines for cosmetic and research ingredients.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. Keep away from strong oxidizers.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC/MS) Conforms
Purity (HPLC) ≥ 95%
Assay ≥ 98%
Loss on Drying ≤ 2.0%
Heavy Metals ≤ 20 ppm
Residual Solvents Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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