Description

2,6-Piperazinedione,1-(Hydroxymethyl)-4-(2-Propynyl)-(9Ci) is a specialized heterocyclic organic compound featuring a piperazinedione core functionalized with hydroxymethyl and propargyl groups. This unique molecular architecture makes it a valuable high-purity building block for advanced chemical synthesis, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for creating novel active pharmaceutical ingredients (APIs) and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new therapeutic agents, particularly for targeted therapies.
• Chemical Biology Probe Synthesis: Utilized in constructing molecular probes and tools for studying biological pathways and protein interactions, leveraging its propargyl group for "click chemistry" applications.
• Peptidomimetic Research: Acts as a constrained scaffold or a modified amino acid analog in the design of peptidomimetics to enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands and organocatalysts for asymmetric synthesis and other advanced chemical transformations.
• Academic and Industrial R&D: Used in exploratory chemistry within university laboratories and corporate R&D centers for novel compound library generation.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific advanced intermediates.

Basic Information

Item	Detail
Product Name	2,6-Piperazinedione,1-(Hydroxymethyl)-4-(2-Propynyl)-(9Ci)
CAS No.	455311-32-7
Molecular Formula	C8H10N2O3
Molecular Weight	182.18 g/mol
Synonyms	1-(Hydroxymethyl)-4-(prop-2-yn-1-yl)piperazine-2,6-dione; 4-Propargyl-1-hydroxymethyl-2,6-piperazinedione; 1-Hydroxymethyl-4-(2-propynyl)-2,6-piperazinedione; (9CI) 2,6-Piperazinedione, 1-(hydroxymethyl)-4-(2-propynyl)-; Propargyl-modified hydroxymethyl piperazinedione; 1-(Hydroxymethyl)-4-(prop-2-ynyl)piperazine-2,6-dione
EINECS	Contact for details

Quality Control

Our 2,6-Piperazinedione,1-(Hydroxymethyl)-4-(2-Propynyl)-(9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our clients' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.