Description

2-Amino-5-Chloro-6-Methylpyrazine is a high-purity pyrazine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific heterocyclic functionality into complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides where the pyrazine core imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional dyes.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects requiring functionalized pyrazine chemistry.

Basic Information

Product Name	2-Amino-5-Chloro-6-Methylpyrazine
CAS No.	453548-87-3
Molecular Formula	C5H6ClN3
Molecular Weight	143.57 g/mol
Synonyms	5-Chloro-6-methylpyrazin-2-amine; 2-Amino-5-chloro-6-methyl-1,4-diazine; 5-Chloro-2-amino-6-methylpyrazine; 6-Methyl-5-chloropyrazin-2-amine; 2-Pyrazinamine, 5-chloro-6-methyl-; (5-Chloro-6-methylpyrazin-2-yl)amine
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Chloro-6-Methylpyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.