Description

Sodelglitazar is a potent and selective dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist. This compound is of significant interest in pharmaceutical research for its potential to modulate lipid and glucose metabolism. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics for metabolic disorders, including type 2 diabetes and dyslipidemia.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in preclinical and clinical studies for metabolic diseases.
• Mechanism of Action Studies: Used as a selective tool compound to investigate the biological pathways and effects mediated by PPARα and PPARγ receptors.
• Drug Discovery Programs: A critical intermediate or target molecule in the synthesis and screening of new PPAR modulator candidates.
• Analytical Method Development: Employed as a high-purity standard for developing and validating HPLC, LC-MS, and other analytical methods in quality control laboratories.
• Biochemical Assays: Used in in vitro assays to study receptor binding affinity, transactivation, and functional cellular responses.

Basic Information

Product Name	Sodelglitazar
CAS No.	447406-78-2
Molecular Formula	C₁₉H₂₀N₂O₅S
Molecular Weight	388.44 g/mol
Synonyms	DRF 10945; Sodel®; (S)-α-Ethoxy-4-[2-methyl-2-(4-methyl-2-(4-methylthiazol-5-yl)-1,3-thiazol-5-yl)propoxy]benzene propanoic acid; 2-Ethoxy-3-[4-[2-(5-methyl-2-(4-methylthiazol-5-yl)-1,3-thiazol-4-yl)ethoxy]phenyl]propanoic acid; (S)-2-Ethoxy-3-[4-[2-(5-methyl-2-(4-methylthiazol-5-yl)thiazol-4-yl)ethoxy]phenyl]propanoic acid
EINECS	Contact for details

Quality Control

Our Sodelglitazar is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research materials. A detailed Certificate of Analysis (COA) providing results for assay, related substances, residual solvents, and other critical parameters is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.