Description

Bicyclo[2.1.1]Hexane-5-Carboxylic Acid, 2-Methylene-, Methyl Ester is a highly functionalized bicyclic building block of significant interest in advanced organic synthesis. Its unique strained bicyclo[2.1.1]hexane core and reactive methylene ester group make it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for introducing rigid, three-dimensional scaffolds to improve pharmacokinetic properties.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the bicyclic structure can confer unique biological activity and stability.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal and mechanical properties.
• Ligand and Catalyst Development: Employed in the synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis applications.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study enzyme function and biological pathways.
• High-Energy Materials Research: Investigated as a potential precursor in the synthesis of advanced, high-density fuels or energetic materials due to its strained ring system.

Basic Information

Product Name	Bicyclo[2.1.1]Hexane-5-Carboxylic Acid, 2-Methylene-, Methyl Ester
CAS No.	446880-09-7
Molecular Formula	C9H12O2
Molecular Weight	152.19 g/mol
Synonyms	Methyl 2-methylenebicyclo[2.1.1]hexane-5-carboxylate; 2-Methylenebicyclo[2.1.1]hexane-5-carboxylic acid methyl ester; Bicyclo[2.1.1]hexane-5-carboxylic acid, 2-methylene-, methyl ester; 5-(Methoxycarbonyl)bicyclo[2.1.1]hex-2-ene
EINECS	Contact for details

Quality Control

Our Bicyclo[2.1.1]Hexane-5-Carboxylic Acid, 2-Methylene-, Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term storage, maintaining the material at 2-8°C under an inert atmosphere is recommended to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.