Description

3-(Piperazin-1-yl)benzoic acid is a high-purity organic building block featuring a benzoic acid core linked to a piperazine moiety. This bifunctional structure makes it a critical intermediate for synthesizing more complex molecules in advanced research and development. It is primarily utilized by pharmaceutical and agrochemical R&D teams for creating novel active compounds, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its structural versatility to modulate biological activity.
• Chemical Biology & Proteomics: Serves as a versatile linker or spacer in the design of chemical probes, affinity tags, and bioconjugation reagents for studying protein function.
• Material Science: Employed as a monomer or functionalization agent in the synthesis of specialty polymers, coatings, and advanced organic materials.
• Academic & Contract Research: Essential for medicinal chemistry programs in academic institutions and contract research organizations (CROs) exploring new chemical entities.

Basic Information

Product Name	3-(Piperazin-1-yl)benzoic Acid
CAS No.	446831-28-3
Molecular Formula	C11H14N2O2
Molecular Weight	206.24 g/mol
Synonyms	3-(1-Piperazinyl)benzoic Acid; Benzoic acid, 3-(1-piperazinyl)-; 3-Piperazin-1-yl-benzoic acid; 1-(3-Carboxyphenyl)piperazine; 3-Carboxyphenylpiperazine; 446831-28-3; 3-Piperazinobenzoic Acid
EINECS	Contact for details

Quality Control

Our 3-(Piperazin-1-yl)benzoic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.