Description

5-Bromo-2-(Dimethylamino)Pyrazine is a versatile pyrazine derivative, a key heterocyclic building block prized for its functional group arrangement. Its molecular structure makes it a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in drug discovery, agrochemicals, and advanced material science.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides, leveraging its heterocyclic core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Scale-Up: A starting material for contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	5-Bromo-2-(Dimethylamino)Pyrazine
CAS No.	446286-94-8
Molecular Formula	C6H8BrN3
Molecular Weight	202.06 g/mol
Synonyms	2-(Dimethylamino)-5-bromopyrazine; 5-Bromo-N,N-dimethylpyrazin-2-amine; 5-Bromo-2-(dimethylamino)pyrazine; 5-Bromo-2-pyrazinamine, N,N-dimethyl-; 446286-94-8; Pyrazine, 5-bromo-2-(dimethylamino)-
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Dimethylamino)Pyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.