Description

(4-[(2,5-Dichlorophenyl)Sulfonyl]Piperazino)(Phenyl)Methanone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct sulfonyl piperazine ketone structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or infectious diseases.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Employed in the development and scale-up processes for new APIs requiring a (phenylsulfonyl)piperazine moiety.
• Biochemical Tool Compound: May be utilized in biochemical assays and as a probe for investigating specific biological pathways or enzyme inhibition.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the global pharmaceutical industry.

Basic Information

Product Name	(4-[(2,5-Dichlorophenyl)Sulfonyl]Piperazino)(Phenyl)Methanone
CAS No.	446277-99-2
Molecular Formula	C17H16Cl2N2O3S
Molecular Weight	399.29 g/mol
Synonyms	1-[(2,5-Dichlorophenyl)sulfonyl]-4-(benzoyl)piperazine; Phenyl[4-[(2,5-dichlorophenyl)sulfonyl]-1-piperazinyl]methanone; 4-[(2,5-Dichlorobenzene-1-sulfonyl)]-1-(phenylcarbonyl)piperazine; (4-(2,5-Dichlorophenylsulfonyl)piperazin-1-yl)(phenyl)methanone; 446277-99-2; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our (4-[(2,5-Dichlorophenyl)Sulfonyl]Piperazino)(Phenyl)Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and process chemistry. Certificates of Analysis (COA) detailing specifications and test results are provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.