Description

Ethyl 4-(2-(1,1-Dioxido-3-Oxobenzo[D]Isothiazol-2(3H)-Yl)Acetyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and psychiatric disorders. It is essential for research institutions and pharmaceutical manufacturers engaged in drug discovery and process development, where precise molecular architecture and reliable supply are critical.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel therapeutic agents, especially in central nervous system (CNS) drug candidates.
• Drug Discovery & Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Process Chemistry & Scale-Up: Serves as a key raw material for optimizing synthetic routes and scaling up production from laboratory to pilot and commercial scale.
• Reference Standard: Can be utilized as an analytical standard for quality control and method validation in API manufacturing.
• Biochemical Research: Potential use as a tool compound for probing specific biological pathways and enzyme interactions in vitro.

Basic Information

Product Name	Ethyl 4-(2-(1,1-Dioxido-3-Oxobenzo[D]Isothiazol-2(3H)-Yl)Acetyl)Piperazine-1-Carboxylate
CAS No.	445265-08-7
Molecular Formula	C16H19N3O6S
Molecular Weight	381.41 g/mol
Synonyms	Ethyl 4-[2-(1,1-dioxo-3-oxo-1,2-benzothiazol-2(3H)-yl)acetyl]piperazine-1-carboxylate; 2-[2-(4-Ethoxycarbonylpiperazin-1-yl)-2-oxoethyl]-1,2-benzothiazol-3(2H)-one 1,1-dioxide; Benzo[d]isothiazol-3(2H)-one, 2-[2-(4-(ethoxycarbonyl)-1-piperazinyl)-2-oxoethyl]-, 1,1-dioxide; 445265-08-7; UNII-9VU96E4K5C; 9VU96E4K5C
EINECS	Contact for details

Quality Control

Our Ethyl 4-(2-(1,1-Dioxido-3-Oxobenzo[D]Isothiazol-2(3H)-Yl)Acetyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.