Description

T-Butyl-4-(2-Amino-1-Phenylethyl)Piperazine Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its piperazine core and chiral amino phenyl ethyl substituent. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and receptor-targeting therapeutics. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel drug candidates and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting neurological pathways.
• API Synthesis: Used in the research and development of new Active Pharmaceutical Ingredients (APIs) for clinical trials and commercial production.
• Chemical Research: Serves as a versatile precursor in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical labs.

Basic Information

Product Name	T-Butyl-4-(2-Amino-1-Phenylethyl)Piperazine Carboxylate
CAS No.	444892-54-0
Molecular Formula	C17H27N3O2
Molecular Weight	305.42 g/mol
Synonyms	tert-Butyl 4-[(1R)-2-amino-1-phenylethyl]piperazine-1-carboxylate; (R)-tert-Butyl 4-(2-amino-1-phenylethyl)piperazine-1-carboxylate; 1-Boc-4-[(1R)-2-amino-1-phenylethyl]piperazine; 1-(tert-Butoxycarbonyl)-4-[(1R)-2-amino-1-phenylethyl]piperazine; 444892-54-0; T-Butyl-4-(2-Amino-1-Phenylethyl)Piperazine-1-Carboxylate
EINECS	Contact for details

Quality Control

Our T-Butyl-4-(2-Amino-1-Phenylethyl)Piperazine Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity and impurity profiling by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.