Description

1-Boc-4-(2-Amino-1-(4-Chloro-Phenyl)Ethyl)-Piperazine is a high-purity, protected piperazine derivative that serves as a critical building block in modern synthetic organic chemistry. This compound is essential for the efficient and controlled synthesis of complex molecules, particularly in the development of new active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular scaffolds with potential therapeutic or functional properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its structural complexity to create compounds with specific biological activity.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of chemical probes and tools for studying biological pathways and protein interactions.
• Peptidomimetics & Medicinal Chemistry: The Boc-protected amine and piperazine core are valuable for creating peptide mimics and optimizing the pharmacokinetic properties of lead compounds.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke intermediates under cGMP or research-grade conditions.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new synthetic routes in organic chemistry laboratories.

Basic Information

Product Name	1-Boc-4-(2-Amino-1-(4-Chloro-Phenyl)Ethyl)-Piperazine
CAS No.	444892-51-7
Molecular Formula	C17H26ClN3O2
Molecular Weight	339.86 g/mol
Synonyms	1-Boc-4-[2-Amino-1-(4-chlorophenyl)ethyl]piperazine; tert-Butyl 4-[2-Amino-1-(4-chlorophenyl)ethyl]piperazine-1-carboxylate; 4-(2-Amino-1-(4-chlorophenyl)ethyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(2-amino-1-(4-chlorophenyl)ethyl)piperazine; N-Boc-4-(2-amino-1-(4-chlorophenyl)ethyl)piperazine; Piperazine, 1-[(1,1-dimethylethoxy)carbonyl]-4-[2-amino-1-(4-chlorophenyl)ethyl]-; 444892-51-7
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(2-Amino-1-(4-Chloro-Phenyl)Ethyl)-Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can be aligned with research-grade or cGMP standards based on customer requirements, ensuring reliable supply for both development and scale-up phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.