Description

(S)-N4-Benzyl-2-Isobutylpiperazine CAS NO 444892-03-9 is a chiral piperazine derivative of significant interest in advanced organic synthesis and pharmaceutical research. Its value lies in its role as a versatile and stereochemically defined building block for constructing complex molecules with specific biological activity. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral targets.
• Asymmetric Catalyst Ligand Precursor: Used to develop novel chiral ligands for metal-catalyzed asymmetric synthesis, enhancing enantioselectivity in critical bond-forming reactions.
• Agrochemical Research: Serves as a building block for novel chiral compounds with potential herbicidal or insecticidal activity.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme function and receptor interactions due to its defined stereochemistry and modifiable structure.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic & Institutional Research: Employed in university and institutional labs for methodological studies in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Item	Details
Product Name	(S)-N4-Benzyl-2-Isobutylpiperazine
CAS No.	444892-03-9
Molecular Formula	C15H24N2
Molecular Weight	232.36 g/mol
Synonyms	(S)-1-Benzyl-2-(2-methylpropyl)piperazine; (S)-2-Isobutyl-1-(phenylmethyl)piperazine; (S)-N-Benzyl-2-isobutylpiperazine; (2S)-1-Benzyl-2-(2-methylpropyl)piperazine; (S)-1-Benzyl-2-isobutylpiperazine; (S)-N4-Benzyl-2-isobutylpiperazine; (S)-2-(2-Methylpropyl)-1-(phenylmethyl)piperazine
EINECS	Contact for details

Quality Control

Our (S)-N4-Benzyl-2-Isobutylpiperazine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.