Description

tert-Butyl4-(Cyano(Phenyl)Methyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core functionalized with cyano and phenyl groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and oncology therapeutics. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting neurological receptors.
• API Synthesis: Used in the multi-step production of complex Active Pharmaceutical Ingredients (APIs) for clinical trials and commercial manufacturing.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Pre-clinical Development: Supplies material for the production of compounds used in pharmacological and toxicological testing.
• Custom Synthesis: A starting point for the custom manufacturing of specialized fine chemicals and bespoke intermediates.

Basic Information

Product Name	tert-Butyl4-(Cyano(Phenyl)Methyl)Piperazine-1-Carboxylate
CAS No.	444891-21-8
Molecular Formula	C17H23N3O2
Molecular Weight	301.39 g/mol
Synonyms	1-Boc-4-[(Cyanophenyl)methyl]piperazine; 1-(tert-Butoxycarbonyl)-4-[(cyanophenyl)methyl]piperazine; tert-Butyl 4-[(cyanophenyl)methyl]piperazine-1-carboxylate; 4-(Cyanobenzyl)piperazine-1-carboxylic acid tert-butyl ester; BOC-4-(Cyanobenzyl)piperazine; 444891-21-8; 1-Boc-4-(α-cyano)benzylpiperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl4-(Cyano(Phenyl)Methyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each lot, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.