Description

1-Boc-4-(1,2,3,4-Tetrahydroquinolin-8-Yl)Piperazine is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core linked to a tetrahydroquinoline moiety and protected by a Boc (tert-butoxycarbonyl) group. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with potential biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new drug candidates, particularly within therapeutic areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new therapeutic agents.
• Library Synthesis: A valuable scaffold for generating diverse compound libraries in high-throughput screening campaigns.
• Chemical Biology Probes: Employed in the development of molecular probes to study biological pathways and target validation.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	1-Boc-4-(1,2,3,4-Tetrahydroquinolin-8-Yl)Piperazine
CAS No.	444620-74-0
Molecular Formula	C18H25N3O2
Molecular Weight	315.41 g/mol
Synonyms	1-Boc-4-(1,2,3,4-tetrahydro-8-quinolyl)piperazine; tert-Butyl 4-(1,2,3,4-tetrahydroquinolin-8-yl)piperazine-1-carboxylate; 1,1-Dimethylethyl 4-(1,2,3,4-tetrahydro-8-quinolinyl)-1-piperazinecarboxylate; 8-(4-Boc-piperazin-1-yl)-1,2,3,4-tetrahydroquinoline; 1-Boc-4-(8-tetrahydroquinolinyl)piperazine; 444620-74-0; BOC-THPQ-PIPERAZINE
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(1,2,3,4-Tetrahydroquinolin-8-Yl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with the standards expected for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.