Description

(11Br)-8,9,10,11,12,13,14,15-Octahydro-N,n-Dimethyl-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine is a specialized organophosphorus compound featuring a complex, fused polycyclic structure. This compound is of significant interest in advanced chemical synthesis, particularly as a key chiral ligand or catalyst precursor for facilitating challenging asymmetric transformations. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis laboratories seeking to develop novel active ingredients and high-value intermediates.

Application

• Asymmetric Catalysis: Serves as a sophisticated chiral ligand in transition metal-catalyzed reactions, such as hydrogenation, cross-coupling, and C-H activation, to produce enantiomerically pure compounds.
• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel, high-efficacy pesticides and herbicides where specific stereochemistry is required for biological activity.
• Material Science Precursor: Potential application in the synthesis of novel organic frameworks or polymers with specific electronic or structural properties.
• Academic & Industrial R&D: A valuable tool for chemists in universities and corporate research centers exploring new methodologies in synthetic organic chemistry.

Basic Information

Product Name	(11Br)-8,9,10,11,12,13,14,15-Octahydro-N,n-Dimethyl-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine
CAS No.	444311-00-6
Molecular Formula	C22H25BrNO2P
Molecular Weight	446.32 g/mol
Synonyms	8,9,10,11,12,13,14,15-Octahydro-N,N-dimethyl-11-bromodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine; 11-Bromo-DM-DIOP; Bromo-DM-DIOP ligand; (11-Br)-H8-DM-DIOP; (11-Bromo)-tetrahydro-DM-DIOP; Brominated DM-DIOP analog; Dinaphthodioxaphosphepinamine derivative
EINECS	Contact for details

Quality Control

Every batch of our (11Br)-8,9,10,11,12,13,14,15-Octahydro-N,n-Dimethyl-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, which is critical for reproducible results in sensitive catalytic and synthetic applications. A detailed Certificate of Analysis (COA) including chiral purity assessment is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage under an inert atmosphere (e.g., argon or nitrogen) is recommended to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.