Description

3-Piperidinemethanol, 5-Amino-4-Hydroxy-, (3R,4R,5R)-Rel- (9Ci) is a high-purity, stereochemically defined piperidine derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in the unique combination of amino, hydroxy, and hydroxymethyl functional groups on a defined stereochemical framework, enabling the construction of complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules targeting neurological and metabolic pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, especially in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the design and production of advanced, stereospecific pesticides and herbicides where specific chirality impacts biological activity.
• Chemical Research & Development: Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Catalyst & Ligand Preparation: Potential precursor for the synthesis of chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of other high-value, complex fine chemicals and specialty materials.

Basic Information

Product Name	3-Piperidinemethanol, 5-Amino-4-Hydroxy-, (3R,4R,5R)-Rel- (9Ci)
CAS No.	443649-03-4
Molecular Formula	C6H14N2O2
Molecular Weight	146.19 g/mol
Synonyms	(3R,4R,5R)-5-Amino-4-hydroxypiperidine-3-methanol; rel-(3R,4R,5R)-5-Amino-4-hydroxy-3-piperidinemethanol; 5-Amino-4-hydroxy-3-piperidinemethanol (rel-(3R,4R,5R)-); 3-Piperidinemethanol, 5-amino-4-hydroxy-, (3R,4R,5R)-rel-; Amino-hydroxy piperidinemethanol derivative
EINECS	Contact for details

Quality Control

Our 3-Piperidinemethanol, 5-Amino-4-Hydroxy-, (3R,4R,5R)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and stereochemical integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.