Description

3-(4-Boc-Piperazin-1-Yl-Methyl)-5-Trifluoromethylaniline is a high-value, multi-functional chemical building block designed for advanced organic synthesis. This compound is critical for the development of novel pharmaceutical agents and agrochemicals, offering a protected piperazine moiety and a reactive aniline group for precise molecular construction. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced bioactivity and metabolic stability.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study enzyme function and protein-protein interactions in drug discovery.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-(4-Boc-Piperazin-1-Yl-Methyl)-5-Trifluoromethylaniline
CAS No.	442846-59-5
Molecular Formula	C18H26F3N3O2
Molecular Weight	373.42 g/mol
Synonyms	1-Boc-4-[(3-Amino-5-(trifluoromethyl)phenyl)methyl]piperazine; tert-Butyl 4-[(3-amino-5-(trifluoromethyl)phenyl)methyl]piperazine-1-carboxylate; 3-[(4-(tert-Butoxycarbonyl)piperazin-1-yl)methyl]-5-(trifluoromethyl)aniline; 5-Trifluoromethyl-3-(1-Boc-piperazin-4-ylmethyl)aniline; 3-(4-Boc-Piperazin-1-ylmethyl)-5-trifluoromethyl-phenylamine; 442846-59-5; BOC-Pip-CF3-Aniline
EINECS	Contact for details

Quality Control

Every batch of 3-(4-Boc-Piperazin-1-Yl-Methyl)-5-Trifluoromethylaniline is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.