Description

1-[4-(4-Amino-Phenyl)-Piperazin-1-Yl]-Propan-1-One is a high-purity, functionalized piperazine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an amino-phenyl group and a propanone moiety, makes it a versatile intermediate for constructing complex pharmacologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its piperazine core.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides where its aromatic amine functionality is incorporated into active structures.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized azo dyes and organic pigments, leveraging its diazotizable amino group.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers with tailored thermal or mechanical properties.

Basic Information

Product Name	1-[4-(4-Amino-Phenyl)-Piperazin-1-Yl]-Propan-1-One
CAS No.	442549-70-4
Molecular Formula	C13H19N3O
Molecular Weight	233.31 g/mol
Synonyms	1-[4-(4-Aminophenyl)piperazin-1-yl]propan-1-one; 1-Propanone, 1-[4-(4-aminophenyl)-1-piperazinyl]-; 4-(4-Aminophenyl)-1-(1-oxopropyl)piperazine; 1-(4-(4-Aminophenyl)piperazin-1-yl)propan-1-one; N-(4-Aminophenyl)-N'-(propionyl)piperazine; CAS 442549-70-4
EINECS	Contact for details

Quality Control

Our 1-[4-(4-Amino-Phenyl)-Piperazin-1-Yl]-Propan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.