Description

Remogliflozin Etabonate is a potent and selective inhibitor of the sodium-glucose cotransporter 2 (SGLT2), developed as an active pharmaceutical ingredient (API). This compound is of significant interest for its role in the research and development of novel therapeutics for managing type 2 diabetes. It is primarily utilized by pharmaceutical manufacturers, research institutions, and contract development and manufacturing organizations (CDMOs) engaged in metabolic disease drug discovery and formulation.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in the formulation of anti-diabetic medications.
• Critical raw material for pharmaceutical research and development targeting SGLT2 inhibition.
• Used in preclinical and clinical studies to investigate pharmacokinetics and pharmacodynamics.
• Reference standard for analytical method development and validation in quality control laboratories.
• Key intermediate in the synthesis of related chemical entities for structure-activity relationship (SAR) studies.
• Supplied to contract manufacturers for the production of finished dosage forms.

Basic Information

Product Name	Remogliflozin Etabonate
CAS No.	442201-24-3
Molecular Formula	C23H30O6S
Molecular Weight	434.55 g/mol
Synonyms	Remogliflozin etabonate; GSK-189075; 5-Methyl-4-({4-[(1S)-2,3,4,5-tetrahydro-1-benzoxepin-1-yl]butyl}oxy)thiophene-2-carboxylic acid 1-({[(ethoxy)carbonyl]oxy}methyl)cyclopentyl ester; 1-({[(Ethoxycarbonyl)oxy]methyl})cyclopentyl 5-methyl-4-({4-[(1S)-2,3,4,5-tetrahydro-1-benzoxepin-1-yl]butyl}oxy)thiophene-2-carboxylate; GSK189075; SGLT2 Inhibitor GSK189075
EINECS	Contact for details

Quality Control

Our Remogliflozin Etabonate is manufactured under strict quality systems to ensure it meets the high-purity standards required for pharmaceutical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ICH guidelines for stability and impurity characterization, ensuring consistency and reliability for your R&D and manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single unknown impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.