Description

tert-Butyl 3-(Hydroxymethyl)-3-(Prop-2-En-1-Yl)Piperidine-1-Carboxylate is a high-value, multi-functional piperidine derivative featuring both a hydroxymethyl and an allyl group, making it a versatile building block for advanced organic synthesis. This compound is critical for research and development in pharmaceutical chemistry, where it serves as a key intermediate for constructing complex molecular architectures. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research pipelines.
• Medicinal Chemistry Building Block: The reactive hydroxymethyl and allyl groups enable diverse chemical modifications, facilitating structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging the piperidine scaffold for biological activity.
• Peptidomimetic Research: Acts as a constrained scaffold to mimic peptide structures, useful in designing enzyme inhibitors and receptor modulators.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds or probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules under cGMP conditions where required.

Basic Information

Product Name	tert-Butyl 3-(Hydroxymethyl)-3-(Prop-2-En-1-Yl)Piperidine-1-Carboxylate
CAS No.	441773-93-9
Molecular Formula	C14H25NO3
Molecular Weight	255.35 g/mol
Synonyms	1-Boc-3-(hydroxymethyl)-3-(2-propen-1-yl)piperidine; 3-(Hydroxymethyl)-3-(2-propen-1-yl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 3-(hydroxymethyl)-3-allylpiperidine-1-carboxylate; 3-Allyl-3-(hydroxymethyl)piperidine-1-carboxylic acid tert-butyl ester; 1-N-Boc-3-(hydroxymethyl)-3-allylpiperidine; 441773-93-9; Boc-3-(hydroxymethyl)-3-allylpiperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(Hydroxymethyl)-3-(Prop-2-En-1-Yl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production can be aligned with cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere such as nitrogen to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.