Description

tert-Butyl4-(3-Cyano-2-Pyridinyl)-1-Piperazinecarboxylate is a high-value pharmaceutical intermediate and building block featuring a piperazine core substituted with a cyano-pyridinyl group and a Boc-protecting group. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated nitrogen-containing heterocycles. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides that leverage its heterocyclic structure for biological activity.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of diverse compound libraries for screening.
• Academic & Contract Research: Employed in academic laboratories and CROs (Contract Research Organizations) for medicinal chemistry and method development projects.
• API Process Development: Integral in scaling up and optimizing synthetic routes for commercial Active Pharmaceutical Ingredient (API) production.

Basic Information

Product Name	tert-Butyl4-(3-Cyano-2-Pyridinyl)-1-Piperazinecarboxylate
CAS No.	440100-15-2
Molecular Formula	C15H20N4O2
Molecular Weight	288.35 g/mol
Synonyms	1-Boc-4-(3-cyano-2-pyridyl)piperazine; tert-Butyl 4-(3-cyano-2-pyridinyl)piperazine-1-carboxylate; 4-(3-Cyano-2-pyridinyl)-1-piperazinecarboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(3-cyano-2-pyridinyl)piperazine; Boc-4-(3-cyano-2-pyridyl)piperazine; 440100-15-2; 2-(1-Boc-piperazin-4-yl)nicotinonitrile
EINECS	Contact for details

Quality Control

Our production of tert-Butyl4-(3-Cyano-2-Pyridinyl)-1-Piperazinecarboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications, ensuring traceability and documentation for regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.