Description

2-(4-Bromophenoxy)-1-{4-[(4-Fluorophenyl)Sulfonyl]Piperazin-1-Yl}Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct bromophenoxy and fluorophenylsulfonyl piperazine structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules targeting specific receptors. It is primarily needed by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers engaged in developing new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique bromine and fluorine substituents.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel herbicides or fungicides.
• Biochemical Tool Compound: Utilized in academic and industrial research to study enzyme inhibition or receptor binding mechanisms.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring a functionalized piperazine derivative.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects and scale-up development.

Basic Information

Product Name	2-(4-Bromophenoxy)-1-{4-[(4-Fluorophenyl)Sulfonyl]Piperazin-1-Yl}Ethanone
CAS No.	439939-70-5
Molecular Formula	C18H18BrFN2O4S
Molecular Weight	457.31 g/mol
Synonyms	1-[4-[(4-Fluorophenyl)sulfonyl]-1-piperazinyl]-2-(4-bromophenoxy)ethanone; 2-(4-Bromophenoxy)-1-(4-(4-fluorophenylsulfonyl)piperazin-1-yl)ethanone; Ethanone, 2-(4-bromophenoxy)-1-[4-[(4-fluorophenyl)sulfonyl]-1-piperazinyl]-; 439939-70-5; 4-Fluorophenylsulfonyl piperazine bromophenoxy ethanone derivative
EINECS	Contact for details

Quality Control

Our 2-(4-Bromophenoxy)-1-{4-[(4-Fluorophenyl)Sulfonyl]Piperazin-1-Yl}Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ICH Q7 guidelines for active pharmaceutical ingredients (APIs) and advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a dark environment. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.