Description

(R)-1-Boc- 3-Ethyl-Piperazine is a high-purity chiral piperazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules with high enantiomeric purity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Research: Employed in the synthesis of advanced, enantiomerically pure pesticides and herbicides.
• Peptidomimetics & Drug Discovery: Integral for constructing conformationally constrained peptide analogs and molecular scaffolds in medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke fine chemicals.

Basic Information

Product Name	(R)-1-Boc- 3-Ethyl-Piperazine
CAS No.	438050-08-9
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	1-Boc-3-ethyl-(R)-piperazine; tert-Butyl (3R)-3-ethylpiperazine-1-carboxylate; (R)-1-(tert-Butoxycarbonyl)-3-ethylpiperazine; (R)-3-Ethyl-1-Boc-piperazine; (R)-N-Boc-3-ethylpiperazine; (R)-1-N-Boc-3-ethylpiperazine; (3R)-1-[(2-Methylpropan-2-yl)oxycarbonyl]-3-ethylpiperazine; (R)-1-(tert-Butyloxycarbonyl)-3-ethylpiperazine
EINECS	Contact for details

Quality Control

Our (R)-1-Boc- 3-Ethyl-Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.