Description

n-Boc-3-Ethylpiperazine is a high-purity, protected piperazine derivative widely utilized as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs), enabling the precise construction of complex molecular architectures. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the piperazine scaffold contributes to biological efficacy.
• Chemical Research & Development: Serves as a protected amine precursor for parallel synthesis and combinatorial chemistry in academic and industrial R&D labs.
• Peptidomimetics & Bioactive Molecule Construction: Employed in the synthesis of peptide analogs and other bioactive molecules that require a functionalized piperazine core.
• Ligand & Catalyst Development: Useful for creating novel ligands for metal catalysis or as a component in organocatalysts.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up manufacturing under GMP or non-GMP conditions.

Basic Information

Product Name	n-Boc-3-Ethylpiperazine
CAS No.	438049-35-5
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	1-Boc-3-Ethylpiperazine; tert-Butyl 3-ethylpiperazine-1-carboxylate; 3-Ethyl-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-3-ethylpiperazine; N-Boc-3-ethylpiperazine; 3-Ethylpiperazine-1-carboxylic acid tert-butyl ester; Boc-3-Ethylpiperazine
EINECS	Contact for details

Quality Control

Our n-Boc-3-Ethylpiperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects with material suitable for research use, pilot plant, and cGMP manufacturing scales.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the original container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.