Description

6-(4-Methyl-Piperazine-1-Carbonyl)-Cyclohex-3-Enecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperazine-carbonyl functionalized cyclohexene structure. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and other therapeutic areas. It is primarily utilized by research institutions, custom synthesis houses, and pharmaceutical manufacturers engaged in the development of novel drug candidates and fine chemical production.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug molecules, especially in medicinal chemistry research and development.
• API Synthesis: Used as a building block for constructing complex molecular architectures required for Active Pharmaceutical Ingredients (APIs).
• Chemical Research: Employed in academic and industrial R&D for exploring new chemical entities and reaction pathways in organic synthesis.
• Custom Manufacturing: A key material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Process Development: Utilized in the scale-up and optimization of synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	6-(4-Methyl-Piperazine-1-Carbonyl)-Cyclohex-3-Enecarboxylic Acid
CAS No.	436087-12-6
Molecular Formula	C13H20N2O3
Molecular Weight	252.31 g/mol
Synonyms	6-[(4-Methyl-1-piperazinyl)carbonyl]-3-cyclohexene-1-carboxylic Acid; 3-Cyclohexene-1-carboxylic acid, 6-[(4-methyl-1-piperazinyl)carbonyl]-; 6-(4-Methylpiperazine-1-carbonyl)cyclohex-3-ene-1-carboxylic Acid; 6-(4-Methylpiperazinecarbonyl)cyclohex-3-enecarboxylic Acid; CAS 436087-12-6
EINECS	Contact for details

Quality Control

Our 6-(4-Methyl-Piperazine-1-Carbonyl)-Cyclohex-3-Enecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.