Description

1-(4-Fluorobenzyl)Piperazine is a versatile fluorinated piperazine derivative, a key building block in advanced organic synthesis. This compound is valued for its role in introducing the 4-fluorobenzylpiperazine moiety, which is crucial for modulating the biological activity and physicochemical properties of target molecules. It is primarily required by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, where the fluorobenzyl group can enhance stability and bioavailability.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies.
• Ligand and Catalyst Preparation: Employed in the creation of specialized ligands for metal catalysis or as a component in functional materials.
• Custom Synthesis Building Block: Supplied to contract research organizations (CROs) and custom synthesis facilities for proprietary client projects.

Basic Information

Product Name	1-(4-Fluorobenzyl)Piperazine
CAS No.	435345-45-2
Molecular Formula	C11H15FN2
Molecular Weight	194.25 g/mol
Synonyms	4-Fluorobenzylpiperazine; 1-[(4-Fluorophenyl)methyl]piperazine; N-(4-Fluorobenzyl)piperazine; 4-Fluorobenzyl-piperazine; Piperazine, 1-[(4-fluorophenyl)methyl]-; 1-(4-Fluorobenzyl)piperazine dihydrochloride (salt form)
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorobenzyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.