Description

2,2-Diphenyl-1-Piperazin-1-Yl-Ethanone is a high-purity, specialized organic building block featuring a ketone-linked diphenyl and piperazine structure. This compound is valued for its role as a versatile intermediate in advanced pharmaceutical research and fine chemical synthesis. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapies.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents and herbicides, leveraging its structural complexity for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme inhibition and cellular pathways.
• Polymer Science: Acts as a functional monomer or cross-linking agent in the development of specialty polymers with tailored thermal or mechanical properties.
• Academic & Institutional Research: A valuable compound for methodological studies in organic synthesis and heterocyclic chemistry at universities and R&D institutes.

Basic Information

Product Name	2,2-Diphenyl-1-Piperazin-1-Yl-Ethanone
CAS No.	435345-44-1
Molecular Formula	C18H20N2O
Molecular Weight	280.37 g/mol
Synonyms	2,2-Diphenyl-1-(piperazin-1-yl)ethanone; 1-(2,2-Diphenylacetyl)piperazine; Ethanone, 2,2-diphenyl-1-(1-piperazinyl)-; 2,2-Diphenyl-1-piperazin-1-ylethanone; 435345-44-1; Diphenyl(piperazin-1-yl)methanone (tautomeric form); N-(2,2-Diphenylacetyl)piperazine
EINECS	Contact for details

Quality Control

Our 2,2-Diphenyl-1-Piperazin-1-Yl-Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.