Description

(S)-4-Bromo-3-Hydroxybutanoic Acid CAS NO 434935-49-6 is a high-value chiral building block and key synthetic intermediate in organic chemistry. This compound is essential for the stereoselective synthesis of complex molecules, offering precise control over three-dimensional structure, which is critical for biological activity. It is primarily needed by pharmaceutical R&D teams, agrochemical manufacturers, and fine chemical producers for developing active pharmaceutical ingredients (APIs), advanced materials, and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of chiral drugs, particularly statins (cholesterol-lowering agents) and other bioactive molecules requiring the (S)-configuration.
• Agrochemical Synthesis: Used in the production of enantiomerically pure pesticides and herbicides, where the specific stereochemistry enhances efficacy and reduces environmental impact.
• Fine Chemical Production: Serves as a versatile starting material for synthesizing specialty chemicals, flavors, fragrances, and advanced polymers.
• Bioconjugation & Probe Development: Utilized in biochemical research for creating labeled compounds, molecular probes, and bioconjugates due to its reactive bromo and carboxylic acid functional groups.
• Academic & Process Chemistry: A valuable reagent in university and industrial research laboratories for methodological development and scaling up asymmetric synthesis routes.

Basic Information

Product Name	(S)-4-Bromo-3-Hydroxybutanoic Acid
CAS No.	434935-49-6
Molecular Formula	C4H7BrO3
Molecular Weight	183.00 g/mol
Synonyms	(S)-4-Bromo-3-hydroxybutyric acid; (3S)-4-Bromo-3-hydroxybutanoic acid; (S)-4-Bromo-3-hydroxybutanoic acid; (S)-3-Hydroxy-4-bromobutyric acid; 4-Bromo-(S)-3-hydroxybutyric acid; (S)-HBA; Bromohydroxybutyric acid (S-isomer); (S)-BHBA
EINECS	Contact for details

Quality Control

Our (S)-4-Bromo-3-Hydroxybutanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with high-purity standards for research and production. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.