Description

2,6-Piperazinedione,3-Methyl-,(3S)-(9Ci) is a chiral piperazinedione derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a crucial chiral building block and synthetic intermediate for the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of peptidomimetics. The specific stereochemistry (3S) makes it a valuable scaffold for creating enantiomerically pure compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of new therapeutic agents, particularly in oncology and neurology.
• Medicinal Chemistry: Used as a constrained scaffold or building block for designing and synthesizing novel peptidomimetics and small molecule libraries.
• Process Chemistry: Employed in route scouting and scale-up studies for the production of enantiomerically pure APIs.
• Academic Research: Serves as a model compound in studies of asymmetric synthesis, heterocyclic chemistry, and molecular recognition.
• Bioconjugation & Probe Development: Potential use in creating chemical probes or conjugates for biochemical and biophysical studies.

Basic Information

Product Name	2,6-Piperazinedione,3-Methyl-,(3S)-(9Ci)
CAS No.	434314-22-4
Molecular Formula	C5H8N2O2
Molecular Weight	128.13 g/mol
Synonyms	(3S)-3-Methylpiperazine-2,6-dione; (S)-3-Methyl-2,6-piperazinedione; 3-Methylpiperazine-2,6-dione (S-enantiomer); L-3-Methyl-2,6-diketopiperazine; (S)-3-Methyl-2,6-dioxopiperazine; (3S)-3-Methyl-2,6-diketopiperazine; (S)-3-Methylpiperazine-2,6-dione; 434314-22-4
EINECS	Contact for details

Quality Control

Our 2,6-Piperazinedione,3-Methyl-,(3S)-(9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (HPLC), chiral purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage or after opening to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.