Description

2-{[(2-Piperazin-1-Ylethyl)Amino]Methylene}-5-Thien-2-Ylcyclohexane-1,3-Dione is a sophisticated heterocyclic compound featuring a piperazine-thiophene-cyclohexanedione scaffold. This structure is of significant interest for its potential as a key intermediate or pharmacophore in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the presence of the piperazine moiety.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, where the thiophene and dione functionalities can contribute to biological activity.
• Chemical Biology Probe: Acts as a scaffold for creating molecular probes to study enzyme inhibition or protein-ligand interactions in biochemical pathways.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors or ligands for metal-organic frameworks (MOFs) due to its conjugated system and donor atoms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring complex heterocyclic chemistry.

Basic Information

Product Name	2-{[(2-Piperazin-1-Ylethyl)Amino]Methylene}-5-Thien-2-Ylcyclohexane-1,3-Dione
CAS No.	432519-44-3
Molecular Formula	C17H23N3O2S
Molecular Weight	333.45 g/mol
Synonyms	5-(2-Thienyl)-2-[[2-(1-piperazinyl)ethyl]amino]methylene-1,3-cyclohexanedione; 2-[(2-Piperazin-1-ylethylamino)methylene]-5-thiophen-2-ylcyclohexane-1,3-dione; 432519-44-3; 5-Thien-2-yl-2-{[(2-piperazin-1-ylethyl)amino]methylene}cyclohexane-1,3-dione; Piperazine-thiophene-dione derivative
EINECS	Contact for details

Quality Control

Our 2-{[(2-Piperazin-1-Ylethyl)Amino]Methylene}-5-Thien-2-Ylcyclohexane-1,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.