Description

2-(1-Piperazinyl)-3-[2-[3-[(Isopropylamino)Methyl]Phenoxy]Ethoxy]Pyrazine CAS NO 428816-13-1 is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of active pharmaceutical ingredients (APIs) targeting specific receptor pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents. Our supply ensures consistent quality and reliable availability for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Biochemical Research: Used as a reference standard or reagent in pharmacological studies and enzyme inhibition assays.
• API Development: Serves as a core structural component in the development and optimization of Active Pharmaceutical Ingredients (APIs).
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry and organic synthesis programs.

Basic Information

Product Name	2-(1-Piperazinyl)-3-[2-[3-[(Isopropylamino)Methyl]Phenoxy]Ethoxy]Pyrazine
CAS No.	428816-13-1
Molecular Formula	C20H31N5O2
Molecular Weight	373.50 g/mol
Synonyms	3-[2-[3-[(Isopropylamino)Methyl]Phenoxy]Ethoxy]-2-(1-Piperazinyl)Pyrazine; 2-Piperazin-1-yl-3-[2-[3-[(propan-2-ylamino)methyl]phenoxy]ethoxy]pyrazine; UNII-6Q4W5V6W0I; 428816-13-1; 2-(Piperazin-1-yl)-3-(2-{3-[(isopropylamino)methyl]phenoxy}ethoxy)pyrazine
EINECS	Contact for details

Quality Control

Our 2-(1-Piperazinyl)-3-[2-[3-[(Isopropylamino)Methyl]Phenoxy]Ethoxy]Pyrazine is manufactured under strict quality control protocols to ensure it meets the high standards required for pharmaceutical research and development. Each batch is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.