Description

2-[(4-Benzhydryl-1-Piperazinyl)Sulfonyl]-5-Methylphenyl Methyl Ether is a specialized organic compound featuring a benzhydryl-piperazine core linked to a methylphenyl ether via a sulfonyl group. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate for the synthesis of complex active ingredients. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within central nervous system (CNS) and receptor-targeted drug discovery programs.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a critical building block for the development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies, especially for compounds targeting neurological pathways.
• Preclinical and Process Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for candidate drugs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke intermediates under cGMP conditions.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	2-[(4-Benzhydryl-1-Piperazinyl)Sulfonyl]-5-Methylphenyl Methyl Ether
CAS No.	428474-30-0
Molecular Formula	C25H28N2O3S
Molecular Weight	436.57 g/mol
Synonyms	5-Methyl-2-[(4-(diphenylmethyl)-1-piperazinyl)sulfonyl]anisole; 2-[(4-(Diphenylmethyl)-1-piperazinyl)sulfonyl]-5-methylanisole; 4-(Diphenylmethyl)-1-[(2-methoxy-4-methylphenyl)sulfonyl]piperazine; 2-Methoxy-5-methylphenyl 4-(diphenylmethyl)piperazine-1-sulfonate; 428474-30-0; Benzhydryl piperazine sulfonyl methylphenyl methyl ether
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and purity. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with client specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.