Description

2-Chloro-6-(4-Piperidinyloxy)Pyrazine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct heterocyclic structure. This compound matters for its critical role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. Pharmaceutical R&D departments and fine chemical manufacturers need this material to develop and scale up production of next-generation drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Chemical Synthesis Reagent: Used in cross-coupling reactions and nucleophilic substitutions to introduce the piperidinyloxy-pyrazine moiety into more complex molecules.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides, leveraging its heterocyclic activity.
• Material Science: Investigated for the creation of specialized organic ligands and functional materials.
• Academic & Contract Research: Utilized in university and CRO laboratories for medicinal chemistry research and process development studies.

Basic Information

Product Name	2-Chloro-6-(4-Piperidinyloxy)Pyrazine
CAS No.	426830-19-5
Molecular Formula	C9H12ClN3O
Molecular Weight	213.66 g/mol
Synonyms	2-Chloro-6-(piperidin-4-yloxy)pyrazine; 2-Chloro-6-(4-piperidyloxy)pyrazine; 4-((6-Chloropyrazin-2-yl)oxy)piperidine; 6-Chloro-2-(4-piperidinyloxy)pyrazine; Pyrazine, 2-chloro-6-(4-piperidinyloxy)-; 426830-19-5; 2-Chloro-6-piperidin-4-yloxypyrazine
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(4-Piperidinyloxy)Pyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.