Description

2-Chloro-6-(4-n-Boc-Piperidinyloxy)Pyrazine is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex pharmaceutical molecules, particularly in medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Process Chemistry Development: Serves as a key starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Agrochemical Synthesis: Employed in the research and development of novel active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A valuable intermediate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Chloro-6-(4-n-Boc-Piperidinyloxy)Pyrazine
CAS No.	426830-18-4
Molecular Formula	C14H20ClN3O3
Molecular Weight	313.78 g/mol
Synonyms	2-Chloro-6-[(4-{[(1,1-dimethylethoxy)carbonyl]amino}piperidin-1-yl)oxy]pyrazine; 2-Chloro-6-(4-(tert-butoxycarbonylamino)piperidin-1-yloxy)pyrazine; 2-Chloro-6-[(4-{[(tert-butoxy)carbonyl]amino}piperidin-1-yl)oxy]pyrazine; tert-Butyl N-[1-[(2-chloropyrazin-6-yl)oxy]piperidin-4-yl]carbamate; 2-Chloro-6-(4-Boc-aminopiperidin-1-yloxy)pyrazine; 2-Chloro-6-(4-(Boc-amino)piperidin-1-yloxy)pyrazine; 426830-18-4
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(4-n-Boc-Piperidinyloxy)Pyrazine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.