Description

2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(4-ethoxyphenyl)acetamide is a high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. Its molecular structure, featuring a thiazolidinedione core linked to a p-ethoxyaniline moiety, makes it a valuable building block for creating novel bioactive compounds. This product is primarily targeted at R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality intermediates for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting metabolic disorders, inflammation, and central nervous system (CNS) conditions.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or plant growth regulators, leveraging its heterocyclic structure.
• Chemical Biology & Proteomics: Acts as a scaffold or a reactive handle in the design of chemical probes for studying enzyme function and biological pathways.
• Material Science: Investigated as a monomer or additive for specialized polymers with unique thermal or optical properties.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting fundamental research in medicinal and synthetic organic chemistry.

Basic Information

Product Name	2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(4-ethoxyphenyl)acetamide
CAS No.	425648-10-8
Molecular Formula	C₁₃H₁₄N₂O₄S
Molecular Weight	294.33 g/mol
Synonyms	5-[(4-Ethoxyphenyl)carbamoylmethyl]-1,3-thiazolidine-2,4-dione; N-(4-Ethoxyphenyl)-2-(2,4-dioxo-1,3-thiazolidin-5-yl)acetamide; 2-(2,4-Dioxothiazolidin-5-yl)-N-(4-ethoxyphenyl)acetamide; Acetamide, 2-(2,4-dioxo-5-thiazolidinyl)-N-(4-ethoxyphenyl)-; 425648-10-8; Thiazolidinedione derivative; TZD derivative
EINECS	Contact for details

Quality Control

Our 2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(4-ethoxyphenyl)acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.