Description

Piperazine, 1-(Chloroacetyl)-4-(2-Pyrimidinyl)- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and other high-value fine chemicals. It is primarily needed by research and development teams, as well as production chemists, in the pharmaceutical, agrochemical, and life science industries seeking to create new molecular entities with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, or oncology.
• Agrochemical Research: Used in the development of new pesticides, herbicides, or fungicides where the piperazine-pyrimidine scaffold can impart specific biological activity.
• Chemical Biology & Proteomics: Serves as a versatile linker or functional group for modifying biomolecules, creating probes, or developing chemical libraries for high-throughput screening.
• Material Science Precursor: Potential use in synthesizing specialty polymers, ligands for catalysis, or organic electronic materials due to its multifunctional structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	Piperazine, 1-(Chloroacetyl)-4-(2-Pyrimidinyl)- (9Ci)
CAS No.	425634-97-5
Molecular Formula	C10H11ClN4O
Molecular Weight	238.67 g/mol
Synonyms	1-(Chloroacetyl)-4-(pyrimidin-2-yl)piperazine; 4-(2-Pyrimidinyl)-1-(chloroacetyl)piperazine; 1-(2-Chloroacetyl)-4-(2-pyrimidinyl)piperazine; N-(2-Chloroacetyl)-N'-(2-pyrimidinyl)piperazine; 2-[4-(2-Pyrimidinyl)piperazin-1-yl]-2-oxoethyl chloride; Piperazine, 1-(chloroacetyl)-4-(2-pyrimidinyl)-; (Chloroacetyl)(2-pyrimidinyl)piperazine
EINECS	Contact for details

Quality Control

Every batch of Piperazine, 1-(Chloroacetyl)-4-(2-Pyrimidinyl)- (9Ci) is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting your R&D and scale-up activities. A detailed Certificate of Analysis (COA) including results from HPLC, NMR, and mass spectrometry is supplied with each shipment to guarantee it meets your specified requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.