Description

1-[(4-Methoxyphenoxy)Acetyl]-4-(3,4,5-Trimethoxybenzoyl)Piperazine is a high-purity synthetic organic compound featuring a piperazine core functionalized with distinct aryl-acetyl and aryl-carbonyl groups. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate (API intermediate) and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and life sciences industries. The compound's structure is designed to enable the synthesis of novel bioactive molecules targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Medicinal Chemistry Research: Used as a key scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Tool Compound: Potential use in developing probes for studying enzyme inhibition or receptor binding assays.
• Process Chemistry Development: Employed in optimizing scalable synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Custom Synthesis & Contract Manufacturing: A starting material for the custom synthesis of more complex, target-specific molecules for client projects.

Basic Information

Product Name	1-[(4-Methoxyphenoxy)Acetyl]-4-(3,4,5-Trimethoxybenzoyl)Piperazine
CAS No.	423738-22-1
Molecular Formula	C23H28N2O7
Molecular Weight	444.48 g/mol
Synonyms	4-(3,4,5-Trimethoxybenzoyl)-1-[2-(4-methoxyphenoxy)acetyl]piperazine; 1-[2-(4-Methoxyphenoxy)acetyl]-4-(3,4,5-trimethoxybenzoyl)piperazine; UNII-5J0Q6QDD5K; 5J0Q6QDD5K; 423738-22-1; 1-[(4-Methoxyphenoxy)acetyl]-4-(3,4,5-trimethoxybenzoyl)piperazine; 1-(4-Methoxyphenoxyacetyl)-4-(3,4,5-trimethoxybenzoyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-[(4-Methoxyphenoxy)Acetyl]-4-(3,4,5-Trimethoxybenzoyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.