Description

(R)-1-(4-Fluorobenzyl)-3-Methylpiperazine is a high-purity chiral piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries, particularly for projects involving chiral drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel therapeutic agents, including central nervous system (CNS) drugs and receptor-targeted molecules.
• Asymmetric Synthesis: Employed as a chiral ligand or auxiliary in catalytic asymmetric reactions to induce stereoselectivity.
• API Development: Used in research and development for constructing the core piperazine scaffold in potential drug candidates.
• Chemical Research: Serves as a valuable reference standard and building block in academic and industrial organic chemistry research.
• Agrochemical Synthesis: Potential application in the development of advanced, chiral agrochemicals and plant protection agents.

Basic Information

Product Name	(R)-1-(4-Fluorobenzyl)-3-Methylpiperazine
CAS No.	422270-29-9
Molecular Formula	C13H19FN2
Molecular Weight	222.30 g/mol
Synonyms	(R)-1-[(4-Fluorophenyl)methyl]-3-methylpiperazine; (R)-3-Methyl-1-(4-fluorobenzyl)piperazine; (R)-1-(4-Fluorobenzyl)-3-methylpiperazine; (R)-1-(p-Fluorobenzyl)-3-methylpiperazine; (R)-N-[(4-Fluorophenyl)methyl]-3-methylpiperazine; (R)-1-(4-Fluorobenzyl)-3-methyl-piperazine; (R)-3-Methyl-1-(4-fluorobenzyl)piperazine; (R)-1-(4-Fluorobenzyl)-3-methylpiperazine CAS 422270-29-9
EINECS	Contact for details

Quality Control

Our (R)-1-(4-Fluorobenzyl)-3-Methylpiperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical-grade intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.