Description

1-Acetyl-4-(2,4-Difluorobenzyl)Piperazine is a high-purity, functionalized piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active ingredients. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of complex molecules targeting a range of therapeutic and protective applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Research: Used as a building block for developing new fungicides and herbicides, leveraging the difluorobenzyl moiety for enhanced biological activity.
• Chemical Synthesis: Acts as a versatile reagent for introducing the acetyl-piperazine pharmacophore into more complex molecular architectures.
• Life Science Research: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new bioactive compounds.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals.

Basic Information

Product Name	1-Acetyl-4-(2,4-Difluorobenzyl)Piperazine
CAS No.	416894-09-2
Molecular Formula	C13H16F2N2O
Molecular Weight	254.28 g/mol
Synonyms	1-[4-[(2,4-Difluorophenyl)methyl]piperazin-1-yl]ethanone; N-Acetyl-4-(2,4-difluorobenzyl)piperazine; 4-(2,4-Difluorobenzyl)-1-acetylpiperazine; 1-Acetyl-4-(2,4-difluorobenzyl)piperazine; 416894-09-2; N-[4-(2,4-Difluorobenzyl)piperazin-1-yl]acetamide
EINECS	Contact for details

Quality Control

Our 1-Acetyl-4-(2,4-Difluorobenzyl)Piperazine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent quality suitable for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.