Description

tert-Butyl 4-(cyclopropylcarbonyl)-1-piperazinecarboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core functionalized with a cyclopropyl ketone and a tert-butoxycarbonyl (Boc) protecting group. This compound is of significant value for its role as a versatile building block in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including potential candidates for central nervous system (CNS) and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in drug discovery programs.
• CNS Drug Development: Serves as a precursor in the synthesis of potential neuroactive compounds targeting specific receptors.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Chemical Biology: Utilized as a probe or ligand in biochemical and pharmacological studies.
• Process Chemistry: Acts as a critical intermediate in the scale-up and optimization of synthetic routes for candidate drugs.

Basic Information

Product Name	tert-Butyl 4-(Cyclopropylcarbonyl)-1-Piperazinecarboxylate
CAS No.	414910-15-9
Molecular Formula	C13H22N2O3
Molecular Weight	254.33 g/mol
Synonyms	1-Boc-4-(cyclopropanecarbonyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(cyclopropylcarbonyl)piperazine; 4-(Cyclopropylcarbonyl)piperazine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(cyclopropanecarbonyl)piperazine-1-carboxylate; 1-Boc-4-cyclopropanecarbonylpiperazine; 414910-15-9; Piperazine-1-carboxylic acid, 4-(cyclopropylcarbonyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(cyclopropylcarbonyl)-1-piperazinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.