Description

2-Chloro-5-(2-Methoxy-Phenyl)-Pyrazine is a high-purity organic building block with a distinct pyrazine core functionalized with chloro and methoxyphenyl substituents. This compound matters as a versatile and critical intermediate for synthesizing complex molecules in advanced research and development. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers working on novel active ingredients, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Agrochemical Synthesis: Serves as a precursor in the creation of novel herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for biological activity.
• Material Science Research: Used in the development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for charge-transport layers.
• Chemical Biology Probes: Employed as a building block for designing molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	2-Chloro-5-(2-Methoxy-Phenyl)-Pyrazine
CAS No.	412924-03-9
Molecular Formula	C11H9ClN2O
Molecular Weight	220.65 g/mol
Synonyms	2-Chloro-5-(2-methoxyphenyl)pyrazine; 5-(2-Methoxyphenyl)-2-chloropyrazine; 2-Chloro-5-(o-methoxyphenyl)pyrazine; Pyrazine, 2-chloro-5-(2-methoxyphenyl)-; 412924-03-9; 2-Chloro-5-(2'-methoxyphenyl)pyrazine; 2-Chloro-5-(2-methoxy-phenyl)-pyrazine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-(2-Methoxy-Phenyl)-Pyrazine is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.