Description

1-Boc-4-Butylpiperazine is a high-purity, protected piperazine derivative of significant importance in modern synthetic organic chemistry. This compound serves as a versatile and critical building block for the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the piperazine moiety contributes to biological activity.
• Ligand and Catalyst Development: Serves as a foundational structure for creating novel ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics & Bioactive Molecules: Integral for constructing peptidomimetic scaffolds and other bioactive compounds in medicinal chemistry programs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.
• Academic & Industrial Research: A valuable reagent for method development and exploratory chemistry in both academic laboratories and industrial R&D facilities.

Basic Information

Product Name	1-Boc-4-Butylpiperazine
CAS No.	412293-87-9
Molecular Formula	C13H26N2O2
Molecular Weight	242.36 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-4-butylpiperazine; tert-Butyl 4-butylpiperazine-1-carboxylate; 4-Butyl-1-Boc-piperazine; N-Boc-4-butylpiperazine; 1-Boc-4-n-butylpiperazine; Piperazine, 4-butyl-1-[(1,1-dimethylethoxy)carbonyl]-; 412293-87-9; Butylpiperazine Boc derivative
EINECS	Contact for details

Quality Control

Our 1-Boc-4-Butylpiperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.