Description

2-Chloro-6-(4-trans-Aminocyclohexyloxy)Pyrazine is a high-purity, functionalized pyrazine derivative with a distinct stereochemical configuration. This compound matters as a sophisticated and versatile pharmaceutical intermediate and research chemical for the development of novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in medicinal chemistry and custom synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its unique chloro-aminocyclohexyloxy substitution pattern.
• Agrochemical Synthesis: Serves as a precursor for developing novel crop protection agents and pesticides.
• Custom Synthesis & Contract Manufacturing: Employed by fine chemical suppliers for the production of specialized, client-specific compounds.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target engagement.
• Academic Research: A valuable reagent for universities and research institutes exploring new heterocyclic chemistry and synthetic methodologies.

Basic Information

Product Name	2-Chloro-6-(4-trans-Aminocyclohexyloxy)Pyrazine
CAS No.	412290-14-3
Molecular Formula	C10H14ClN3O
Molecular Weight	227.69 g/mol
Synonyms	trans-4-((6-Chloropyrazin-2-yl)oxy)cyclohexanamine; 2-Chloro-6-[(trans-4-aminocyclohexyl)oxy]pyrazine; 6-Chloro-2-[(trans-4-aminocyclohexyl)oxy]pyrazine; 2-Chloro-6-(trans-4-aminocyclohexyloxy)pyrazine; (trans)-4-((6-Chloropyrazin-2-yl)oxy)cyclohexan-1-amine; 412290-14-3; 2-Chloro-6-(4-aminocyclohexyloxy)pyrazine (trans isomer)
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(4-trans-Aminocyhexyloxy)Pyrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high chemical purity and stereochemical integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support development and commercial projects with consistent quality and full traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Isomeric Purity (trans isomer)	≥ 99.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.