Description

1-[(4-Chloro-3-Methoxyphenyl)Sulfonyl]-4-(2-Methoxyphenyl)Piperazine CAS NO 409357-21-7 is a high-purity, synthetic organic compound belonging to the sulfonylated piperazine class. This advanced pharmaceutical intermediate is critical for research and development in medicinal chemistry, offering a versatile scaffold for creating novel therapeutic agents. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of potential drug candidates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted drug discovery programs.
• Medicinal Chemistry Research: Used as a core scaffold in structure-activity relationship (SAR) studies to develop new compounds with optimized pharmacological profiles.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing.
• Biochemical Tool Compound: Potential use in biochemical assays and as a reference standard for studying specific biological pathways and receptor interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the global life sciences sector.

Basic Information

Product Name	1-[(4-Chloro-3-Methoxyphenyl)Sulfonyl]-4-(2-Methoxyphenyl)Piperazine
CAS No.	409357-21-7
Molecular Formula	C18H21ClN2O4S
Molecular Weight	396.89 g/mol
Synonyms	4-(2-Methoxyphenyl)-1-[(4-chloro-3-methoxyphenyl)sulfonyl]piperazine; 1-(4-Chloro-3-methoxyphenylsulfonyl)-4-(2-methoxyphenyl)piperazine; 4-(2-Methoxyphenyl)-1-(4-chloro-3-methoxyphenylsulfonyl)piperazine; 409357-21-7; 1-(4-Chloro-3-methoxy-benzenesulfonyl)-4-(2-methoxy-phenyl)-piperazine; 4-(2-Methoxyphenyl)-1-[(4-chloro-3-methoxyphenyl)sulfonyl]piperazine; Piperazine, 1-[(4-chloro-3-methoxyphenyl)sulfonyl]-4-(2-methoxyphenyl)-
EINECS	Contact for details

Quality Control

Our 1-[(4-Chloro-3-Methoxyphenyl)Sulfonyl]-4-(2-Methoxyphenyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.