Description

Sergliflozin CAS NO 408504-26-7 is a high-purity pharmaceutical intermediate and research chemical belonging to the class of sodium-glucose cotransporter 2 (SGLT2) inhibitors. This compound is of significant interest for its role in the development of novel therapeutic agents targeting metabolic disorders such as type 2 diabetes. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of active pharmaceutical ingredients (APIs) for synthesis and pharmacological studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced SGLT2 inhibitor drug candidates and related analogs.
• Biochemical Research: Used as a reference standard and tool compound in metabolic disease research to study glucose reabsorption mechanisms.
• Preclinical Development: Employed in the early-stage development and optimization of new antidiabetic therapies.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a critical precursor in the multi-step manufacturing process of SGLT2 inhibitor APIs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for pharmacological and medicinal chemistry studies.

Basic Information

Product Name	Sergliflozin
CAS No.	408504-26-7
Molecular Formula	C23H25FO5S
Molecular Weight	432.51 g/mol
Synonyms	Sergliflozin; Sergliflozin (SGLT2 inhibitor); Sergliflozin free base; (1S)-1,5-Anhydro-1-C-[4-ethyl-5-fluoro-2-[(4-methoxyphenyl)methyl]phenyl]-D-glucitol; Sergliflozin (JAN/INN); Sergliflozinum (Latin); Sergliflozina (Spanish/Italian)
EINECS	Contact for details

Quality Control

Our Sergliflozin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with a detailed Certificate of Analysis (COA) that includes results from HPLC, NMR, and MS. Specifications are designed to meet the stringent requirements of pharmaceutical R&D and pre-GMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.