Description

C-[4-(3-Fluoro-Benzyl)-Morpholin-2-Yl]-Methylamine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its dihydrochloride salt form, which enhances stability and handling properties. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting central nervous system disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for neurological and psychiatric applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
• API Development: Serves as a critical precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Preclinical & Clinical Trial Material: Supplied for the production of materials required for non-clinical safety studies and clinical trial batches.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) performing bespoke synthesis for client projects.

Basic Information

Product Name	C-[4-(3-Fluoro-Benzyl)-Morpholin-2-Yl]-Methylamine Dihydrochloride
CAS No.	407640-28-2
Molecular Formula	C₁₃H₁₉Cl₂FN₂O
Molecular Weight	309.21 g/mol
Synonyms	(2R)-2-(Aminomethyl)-4-[(3-fluorophenyl)methyl]morpholine dihydrochloride; (2R)-4-(3-Fluorobenzyl)-2-(aminomethyl)morpholine dihydrochloride; C-[4-(3-Fluoro-Benzyl)-Morpholin-2-Yl]-Methylamine HCl; (2R)-2-(Aminomethyl)-4-(3-fluorobenzyl)morpholine dihydrochloride; 4-(3-Fluorobenzyl)-2-(aminomethyl)morpholine dihydrochloride; 407640-28-2; UNII-9Q6B8S5C0F; BDBM50380957
EINECS	Contact for details

Quality Control

Our C-[4-(3-Fluoro-Benzyl)-Morpholin-2-Yl]-Methylamine Dihydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity determination, and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support compliance with relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.