Description

2,5-Piperazinedione,3-Ethyl-6-(1-Methylethyl)-,(3S,6S)-(9Ci) is a high-purity, stereochemically defined diketopiperazine (DKP) derivative, a privileged scaffold in medicinal chemistry. This compound matters as a sophisticated chiral building block for the synthesis of complex pharmaceutical intermediates and bioactive molecules. It is primarily needed by research and development teams in the pharmaceutical and biotechnology sectors, particularly those focused on peptide mimetics, protease inhibitors, and novel drug discovery programs. The product is supplied under strict quality control, with CAS number 407578-43-2.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), especially in oncology and antiviral research.
• Peptidomimetic Scaffold: Core structure for designing and synthesizing novel peptide analogs with enhanced metabolic stability and bioavailability.
• Protease Inhibitor Research: Building block for creating libraries of compounds targeting specific proteases involved in disease pathways.
• Asymmetric Synthesis: Utilized in stereoselective chemical reactions to introduce complex chiral centers into target molecules.
• Chemical Biology & Probe Development: Used in the synthesis of molecular probes for studying enzyme function and protein-protein interactions.
• Academic & Industrial R&D: Serves as a high-value reference standard and starting material in exploratory chemistry for new therapeutic entities.

Basic Information

Product Name	2,5-Piperazinedione,3-Ethyl-6-(1-Methylethyl)-,(3S,6S)-(9Ci)
CAS No.	407578-43-2
Molecular Formula	C9H16N2O2
Molecular Weight	184.24 g/mol
Synonyms	(3S,6S)-3-Ethyl-6-isopropylpiperazine-2,5-dione; (3S,6S)-3-Ethyl-6-(1-methylethyl)-2,5-piperazinedione; (3S,6S)-3-Ethyl-6-isopropyl-2,5-diketopiperazine; (S,S)-3-Ethyl-6-isopropylpiperazine-2,5-dione; Cyclo(L-isoleucyl-L-isoleucyl); Diketopiperazine derivative; DKP; Chiral Diketopiperazine; CAS 407578-43-2
EINECS	Contact for details

Quality Control

Our 2,5-Piperazinedione,3-Ethyl-6-(1-Methylethyl)-,(3S,6S)-(9Ci) is manufactured under a quality management system and undergoes rigorous analytical testing to ensure batch-to-batch consistency and high purity. Certificates of Analysis (COA) are provided with each shipment, detailing specifications for identity, purity, chiral purity, and impurity profiles. We support development and cGMP-grade requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (3S,6S)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.