Description

Piperazine, 1-[(1E)-2-Phenylethenyl]- (9Ci) is a specialized piperazine derivative featuring a styryl substituent, which imparts unique chemical reactivity and structural properties. This compound is a valuable pharmacophore and synthetic intermediate in advanced organic synthesis, enabling the construction of complex molecules for research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on creating novel bioactive compounds, including potential drug candidates and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic core for bioactivity.
• Organic Synthesis Reagent: Acts as a versatile reactant for constructing complex nitrogen-containing heterocycles and functionalized piperazine scaffolds in academic and industrial labs.
• Material Science Precursor: Potential use in the synthesis of specialty polymers, ligands for catalysis, or advanced organic materials requiring specific piperazine motifs.
• Bioconjugation & Chemical Biology: The reactive styryl group can be utilized for click chemistry or other conjugation strategies in probe and linker development.

Basic Information

Product Name	Piperazine, 1-[(1E)-2-Phenylethenyl]- (9Ci)
CAS No.	405872-83-5
Molecular Formula	C12H16N2
Molecular Weight	188.27 g/mol
Synonyms	1-[(1E)-2-Phenylethenyl]piperazine; (E)-1-Styrylpiperazine; 1-[(E)-Styryl]piperazine; 1-(2-Phenylethenyl)piperazine; 405872-83-5; 1-(2-Phenylethenyl)piperazine (E)-; 1-(2-Phenylethenyl)piperazine, (E)-; 1-(2-Phenylethenyl)piperazine, (E)-isomer
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity for research and development applications. Our products undergo comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality parameters. We support compliance with relevant ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term stability if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.